DAB2 antibody [C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||82 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)|
|Product Description||Rabbit polyclonal antibody to DAB2 (disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila))|
|Background||DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta). [provided by RefSeq]|
|Synonyms||DOC-2 antibody, DOC2 antibody, FLJ26626 antibody, DAB2 antibody, differentially-expressed protein 2 antibody, disabled homolog 2 antibody, "disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) antibody"|
|Cellular Localization||Cytoplasmic vesicle , clathrin-coated vesicle membrane , Membrane , clathrin-coated pit |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DAB2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (85%)|