|Full Name||eukaryotic translation initiation factor 4 gamma, 2|
|Product Description||Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2)|
|Background||Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]|
|Synonyms||AAG1 antibody, DAP5 antibody, FLJ41344 antibody, NAT1 antibody, P97 antibody, EIF4G2 antibody, death-associated protein 5 antibody, eukaryotic translation initiation factor 4G-like 1 antibody, DAP-5 antibody, eukaryotic translation initiation factor 4 gamma 2 antibody, eIF-4G 2 antibody, aging-associated protein 1 antibody, eIF4G 2 antibody, eIF-4-gamma 2 antibody, eukaryotic translation initiation factor 4 gamma, 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human DAP5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (91%), Rabbit (100%), Chicken (99%), Bovine (100%)|