|Full Name||deleted in azoospermia-like|
|Product Description||Rabbit polyclonal antibody to DAZL (deleted in azoospermia-like)|
|Background||The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. [provided by RefSeq]|
|Synonyms||DAZH antibody, DAZL1 antibody, DAZLA antibody, MGC26406 antibody, SPGYLA antibody, DAZL antibody, germline specific RNA binding protein antibody, deleted in azoospermia-like 1 antibody, SPGY-like-autosomal antibody, deleted in azoospermia-like antibody, DAZ homolog antibody, spermatogenesis gene on the Y-like autosomal antibody, DAZ-like autosomal antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DAZL. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%), Bovine (100%)|