|Full Name||dihydrolipoamide branched chain transacylase E2|
|Product Description||Rabbit Polyclonal antibody to DBT (dihydrolipoamide branched chain transacylase E2)|
|Background||The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||BCATE2 antibody, E2 antibody, E2B antibody, MGC9061 antibody, DBT antibody, BCKAD E2 subunit antibody, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase antibody, dihydrolipoyl transacylase antibody, mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b) antibody, lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial antibody, branched chain acyltransferase, E2 component antibody, BCKAD-E2 antibody, dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody, branched-chain alpha-keto acid dehydrogenase complex component E2 antibody, lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex antibody, BCKADE2 antibody, E2 component of branched chain alpha-keto acid dehydrogenase complex antibody, dihydrolipoamide branched chain transacylase E2 antibody|
|Cellular Localization||Mitochondrion matrix|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DBT. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (82%), Xenopus laevis (89%), Chicken (85%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (96%)|