|Full Name||NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to DC8 (NSL1, MIND kinetochore complex component, homolog (S. cerevisiae))|
|Background||This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||C1orf48 antibody, DKFZp566O1646 antibody, MIS14 antibody, NSL1 antibody, kinetochore-associated protein NSL1 homolog antibody, NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) antibody|
|Cellular Localization||Nucleus , Kinetochore |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DC8. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (87%)|