|Full Name||dynactin 3 (p22)|
|Product Description||Rabbit Polyclonal antibody to DCTN3 (dynactin 3 (p22))|
|Background||This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]|
|Synonyms||DCTN-22 antibody, DCTN22 antibody, MGC111190 antibody, DCTN3 antibody, "dynactin 3, isoform 1 antibody", dynactin complex subunit 22 kDa subunit antibody, p22 antibody, dynactin light chain antibody, dynactin subunit 3 antibody, dynactin 3 (p22) antibody|
|Cellular Localization||Cytoplasm , Centrosome , Kinetochore , Spindle |
|Immunogen||Full length human DCTN3 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (84%), Bovine (80%)|