|Full Name||DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)|
|Product Description||Rabbit polyclonal antibody to DCUN1D1 (DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae))|
|Background||Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.|
|Synonyms||DCUN1L1 antibody, RP42 antibody, SCCRO antibody, SCRO antibody, Tes3 antibody, DCUN1D1 antibody, RP42 homolog antibody, DCUN1 domain-containing protein 1 antibody, DCN1-like protein 1 antibody, squamous cell carcinoma-related oncogene antibody, defective in cullin neddylation protein 1-like protein 1 antibody, "DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DCUN1D1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (81%), Zebrafish (88%), Xenopus laevis (97%), Chicken (98%), Rhesus Monkey (100%), Bovine (93%)|