|Full Name||DEAD (Asp-Glu-Ala-Asp) box polypeptide 21|
|Product Description||Rabbit Polyclonal antibody to DDX21 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 21)|
|Background||DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq]|
|Synonyms||DKFZp686F21172 antibody, GUA antibody, GURDB antibody, RH-II/GU antibody, RH-II/GuA antibody, DDX21 antibody, nucleolar RNA helicase Gu antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21 antibody, nucleolar RNA helicase 2 antibody, Gu protein antibody, DEAD box protein 21 antibody, gu-alpha antibody, nucleolar RNA helicase II antibody, RNA helicase II/Gu alpha antibody, RH II/Gu antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antibody|
|Cellular Localization||Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DDX21. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Sheep, Bovine|
|Predict Reactivity Note||Mouse (86%), Rat (86%), Sheep (89%), Bovine (88%)|