Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||73 kDa (note)
|Positive Controls||H1299 , HepG2 , mouse brain , rat testis , Jurkat , Raji , NCI-H929|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked|
|Product Description||Rabbit Polyclonal antibody to DDX3 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked)|
|Background||DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||DBY antibody, DDX3Y antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome antibody, DEAD box protein 3, Y-chromosomal antibody, ATP-dependent RNA helicase DDX3Y antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DDX3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rhesus Monkey (99%), Chimpanzee (97%), Bovine (94%)|