|Full Name||death effector domain containing|
|Product Description||Rabbit Polyclonal antibody to DEDD (death effector domain containing)|
|Background||This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||KE05 Antibody , DEFT Antibody , FLDED1 Antibody , DEDD1 Antibody , CASP8IP1 Antibody , death effector domain containing Antibody|
|Cellular Localization||Cytoplasm , Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Xenopus laevis (86%), Rhesus Monkey (99%), Bovine (97%)|