DEDD antibody [N3C2], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||death effector domain containing|
|Product Description||Rabbit Polyclonal antibody to DEDD (death effector domain containing)|
|Background||This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||CASP8IP1 antibody, DEDD1 antibody, DEFT antibody, FLDED1 antibody, DEDD antibody, death effector domain-containing testicular molecule antibody, FLDED-1 antibody, DEDPro1 antibody, death effector domain-containing protein antibody, death effector domain containing antibody|
|Cellular Localization||Cytoplasm , Nucleus , nucleolus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)|