| Full Name | DiGeorge syndrome critical region gene 2 |
| Product Description | Rabbit Polyclonal antibody to DGCR2 (DiGeorge syndrome critical region gene 2) |
| Background | Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. [provided by RefSeq] |
| Synonyms | DGS-C antibody, DKFZp686I1730 antibody, IDD antibody, KIAA0163 antibody, LAN antibody, SEZ-12 antibody, DGCR2 antibody, DiGeorge syndrome critical region protein 2 antibody, integral membrane protein deleted in DiGeorge syndrome antibody, integral membrane protein DGCR2/IDD antibody, DiGeorge syndrome critical region gene 2 antibody |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DGCR2. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Xenopus laevis, Bovine |
| Predict Reactivity Note | Mouse (97%), Rat (97%), Xenopus laevis (80%), Bovine (90%) |
| Conjugation | Unconjugated |