|Full Name||diaphanous homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to DIAPH1 (diaphanous homolog 1 (Drosophila))|
|Background||This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DFNA1 antibody, DIA1 antibody, DRF1 antibody, FLJ25265 antibody, LFHL1 antibody, hDIA1 antibody, DIAPH1 antibody, protein diaphanous homolog 1 antibody, diaphanous-related formin-1 antibody, diaphanous-related formin 1 antibody, diaphanous homolog 1 (Drosophila) antibody|
|Cellular Localization||Cell membrane , Cell projection , ruffle membrane , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human DIAPH1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (94%), Pig (88%)|