DIAPH1 antibody [N1N2], N-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||141 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||diaphanous homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to DIAPH1 (diaphanous homolog 1 (Drosophila))|
|Background||This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DFNA1 antibody, DIA1 antibody, DRF1 antibody, FLJ25265 antibody, LFHL1 antibody, hDIA1 antibody, DIAPH1 antibody, protein diaphanous homolog 1 antibody, diaphanous-related formin-1 antibody, diaphanous-related formin 1 antibody, diaphanous homolog 1 (Drosophila) antibody|
|Cellular Localization||Cell membrane , Cell projection , ruffle membrane , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human DIAPH1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig|
|Predict Reactivity Note||Mouse (95%), Rat (94%), Pig (96%)|