|Full Name||diaphanous homolog 3 (Drosophila)|
|Product Description||Rabbit polyclonal antibody to DIAPH3 (diaphanous homolog 3 (Drosophila))|
|Background||Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.|
|Synonyms||DKFZp434C0931 antibody, DKFZp686A13178 antibody, DRF3 antibody, FLJ34705 antibody, diap3 antibody, mDia2 antibody, DIAPH3 antibody, diaphanous-related formin-3 antibody, diaphanous-related formin 3 antibody, "auditory neuropathy, autosomal dominant 1 antibody", protein diaphanous homolog 3 antibody, diaphanous homolog 3 (Drosophila) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (86%), Rat (84%), Bovine (90%)|