|Full Name||diaphanous homolog 3 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to DIAPH3 (diaphanous-related formin 3)|
|Background||Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. |
|Synonyms||diaphanous homolog 3 (Drosophila) Antibody , DIA2 Antibody , diap3 Antibody , AUNA1 Antibody , NSDAN Antibody , mDia2 Antibody , DRF3 Antibody , AN Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (82%)|