|Full Name||disrupted in schizophrenia 1|
|Product Description||Rabbit Polyclonal antibody to DISC1 (disrupted in schizophrenia 1)|
|Background||This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||C1orf136 antibody, FLJ13381 antibody, FLJ21640 antibody, FLJ25311 antibody, FLJ41105 antibody, KIAA0457 antibody, SCZD9 antibody, DISC1 antibody, disrupted in schizophrenia 1 protein antibody, disrupted in schizophrenia 1 antibody|
|Cellular Localization||Cytoplasm , Centrosome , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human DISC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (95%)|