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1 .GTX59723 DKK1 antibody

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DKK1 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX59723
Package Price Qty
100 μgUSD 329.00
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  • Anti-DKK1 antibody used in Western Blot (WB). GTX59723
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  • Datasheet
  • Application Information: DKK1 antibody

Catalog Number GTX59723
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Product Name DKK1 antibody
See all DKK1 products
ApplicationsWB
Application NoteWestern blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~35 kDa Dkk1 of human, mouse and rat origins.
Form SuppliedLiquid
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration)
PurificationAffinity purified

  • Specifications: DKK1 antibody

Full Namedickkopf homolog 1 (Xenopus laevis)
BackgroundXenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of Dkk1 and Dkk2 inhibited Wnt-3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of Dkk-2, but not that of Dkk-1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl.
SynonymsDKK-1, DKK1, dickkopf1 like, dickkopf1, dickkopf homolog 1, dickkopf-1, dickkopf homolog1, SK, dickkopf-1 like, DKK 1, dickkopf 1, dickkopf 1 like
SpecificityThis antibody is specific for DKK1.
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: DKK1 antibody

Storage BufferPBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Storage InstructionThe antibody solution should be gently mixed before use. Stored at -20 °C for future use.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Neuroscience > Disorder > Alzheimer's disease
  • Neuroscience > Signaling > Wnt singnaling
  • Signal Transduction > Signaling through proteolysis > Wnt
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DKK1 antibody validated data
  • Anti-DKK1 antibody used in Western Blot (WB). GTX59723
    • GTX59723 WB Image
      Western blot analysi s of Dkk1 in Lysates from 3T3 cells (Lane 1) and rat kidney (Lane 2).
      Top
  • Anti-DKK1 antibody used in Western Blot (WB). GTX59723
    • GTX59723 WB Image
      Western blot analysi s of Dkk1 in Lysates from 3T3 cells (Lane 1) and rat kidney (Lane 2).
      Top
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