|Full Name||dihydrolipoamide S-acetyltransferase|
|Product Description||Rabbit Polyclonal antibody to DLAT (dihydrolipoamide S-acetyltransferase)|
|Background||The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 188.8.131.52), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC; EC 184.108.40.206) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC; MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]|
|Synonyms||DLTA antibody, PDC-E2 antibody, PDCE2 antibody, DLAT antibody, "dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial antibody", pyruvate dehydrogenase complex component E2 antibody, dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex antibody, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis antibody, M2 antigen complex 70 kDa subunit antibody, dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial antibody, PBC antibody, E2 component of pyruvate dehydrogenase complex antibody, dihydrolipoamide S-acetyltransferase antibody|
|Cellular Localization||Mitochondrion matrix|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DLAT. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (87%), Pig (91%), Rhesus Monkey (98%), Bovine (93%)|