|Full Name||doublesex and mab-3 related transcription factor 1|
|Product Description||Rabbit Polyclonal antibody to DMRT1 (doublesex and mab-3 related transcription factor 1)|
|Background||This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq]|
|Synonyms||DMT1 antibody, DMRT1 antibody, DM domain expressed in testis 1 antibody, doublesex- and mab-3-related transcription factor 1 antibody, DM domain expressed in testis protein 1 antibody, doublesex and mab-3 related transcription factor 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DMRT1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (84%)|