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1 .GTX109069 DNA Polymerase epsilon p59 antibody

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DNA Polymerase epsilon p59 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsDot
  • Species reactivityHuman
  • Publication  ( 1 )
Cat No: GTX109069
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Application Information: DNA Polymerase epsilon p59 antibody

Catalog Number GTX109069
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( 0 )
Publication ( 1 )
Product Name DNA Polymerase epsilon p59 antibody
See all DNA Polymerase epsilon p59 products
ApplicationsDot
Application Note
Suggested dilutionReference
Dot blotAssay-dependent dilution Y
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size60 kDa (note) IsoForm (4)
Positive ControlsTarget recombinant protein
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: DNA Polymerase epsilon p59 antibody

Full Namepolymerase (DNA directed), epsilon 2 (p59 subunit)
BackgroundParticipates in DNA repair and in chromosomal DNA replication.
SynonymsDPE2 antibody, POLE2 antibody, DNA polymerase epsilon subunit B antibody, DNA polymerase epsilon subunit 2 antibody, DNA polymerase II subunit 2 antibody, "polymerase (DNA directed), epsilon 2 (p59 subunit) antibody"
Cellular LocalizationNucleus
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein encompassing a sequence within the center region of human DNA Polymerase epsilon p59. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
Mouse, Rat, Xenopus laevis, Bovine
Predict Reactivity NoteMouse (91%), Rat (91%), Xenopus laevis (82%), Bovine (95%)
ConjugationUnconjugated

  • Storage Conditions: DNA Polymerase epsilon p59 antibody

Storage Buffer0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > DNA repair > Nucleotide-excision repair > DNA gap filling
  • Cancer > Type of cancer > Urogenital > Urinary Bladder
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DNA Polymerase epsilon p59 antibody validated data
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  • Reference for DNA Polymerase epsilon p59 antibody
Application References Application Reactivity
Li CM et al. Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis. PLoS One 11 (12):e0169259 (2016). Dot Human
Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensPOLE25427P56282602670NP_00133531359.46
Homo sapiensPOLE25427P56282602670NM_001197330NP_00118425956.43
Homo sapiensPOLE25427P56282602670NM_001197331NP_00118426056.79
Homo sapiensPOLE25427P56282602670NM_002692NP_00268359.55

Cross-react Bioinfo
SpeciesGene nameGene IDSwissProtIsoform (mRNA)Protein Accession#MW
Mus musculusPole218974O54956NM_011133NP_03526359.4
Rattus norvegicusPole2299112NM_001169108NP_00116257959.21
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-Thimerosal.pdf
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