DNA ligase I antibody [C2C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||102 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||ligase I, DNA, ATP-dependent|
|Product Description||Rabbit polyclonal antibody to DNA ligase I (ligase I, DNA, ATP-dependent)|
|Background||LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq]|
|Synonyms||MGC117397 antibody, MGC130025 antibody, LIG1 antibody, polydeoxyribonucleotide synthase ATP 1 antibody, polydeoxyribonucleotide synthase [ATP] 1 antibody, DNA ligase 1 antibody, "ligase I, DNA, ATP-dependent antibody"|
|Cellular Localization||Nucleus |
|Target||DNA ligase I|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase I. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (91%), Rat (91%), Bovine (89%)|