DNA polymerase beta antibody
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||38 kDa (note)
|Positive Controls||human POLB-transfected 293T cells (no boiling) , *MCF7 , *MDA-MB-231 , *MDA-MB-361 , *MDA-MB-453 , *T47D , *ZR-75-1 , *293T , *HeLa , *HT29 , *U2OS |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||polymerase (DNA directed), beta|
|Product Description||Rabbit Polyclonal antibody to DNA polymerase beta (polymerase (DNA directed), beta)|
|Background||In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance. Also see POLA (MIM 312040).[supplied by OMIM]|
|Synonyms||POLB Antibody, polymerase (DNA directed), beta Antibody|
|Cellular Localization||Nucleus |
|Target||DNA polymerase beta|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DNA polymerase beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (94%), Zebrafish (83%), Xenopus laevis (83%), Rhesus Monkey (99%), Bovine (97%)|