|Full Name||deoxyribonuclease II beta|
|Product Description||Rabbit Polyclonal antibody to DNASE2B (deoxyribonuclease II beta)|
|Background||The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||DLAD antibody, DNASE2B antibody, lysosomal DNase II antibody, DNase2-like acid DNase antibody, endonuclease DLAD antibody, deoxyribonuclease-2-beta antibody, DNase II beta antibody, DNase II-like acid DNase antibody, deoxyribonuclease II beta antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DNASE2B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (88%)|