|Full Name||DNA (cytosine-5-)-methyltransferase 3 alpha|
|Product Description||Rabbit Polyclonal antibody to DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha)|
|Background||CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||DNMT3A2 antibody, M.HsaIIIA antibody, DNMT3A antibody, DNA (cytosine-5)-methyltransferase 3A antibody, DNA cytosine methyltransferase 3A2 antibody, DNA MTase HsaIIIA antibody, DNA (cytosine-5-)-methyltransferase 3 alpha antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DNMT3A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (100%)|