|Full Name||dedicator of cytokinesis 1|
|Product Description||Goat polyclonal antibody to DOCK1|
|Background||Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1. |
|Synonyms||dedicator of cytokinesis1, DOCK180, dedicator of cytokinesis 1, RP1182L9.1, DOCK1, RP11-82L9.1, ced5, dedicator of cyto-kinesis 1, dedicator of cyto kinesis 1|
|Cellular Localization||Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-triphosphate. |
|Specificity||This antibody is specific for DOCK1.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|