|Full Name||dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit|
|Product Description||Rabbit Polyclonal antibody to DPM1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit)|
|Background|| Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq]|
|Synonyms||CDGIE antibody, MPDS antibody, DPM1 antibody, DPM synthase antibody, dolichol monophosphate mannose synthase antibody, MPD synthase antibody, dolichyl-phosphate beta-D-mannosyltransferase antibody, dolichol-phosphate mannosyltransferase antibody, dolichol-phosphate mannose synthase antibody, mannose-P-dolichol synthase antibody, "dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antibody"|
|Cellular Localization||Endoplasmic reticulum|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (88%), Rat (89%), Pig (92%), Bovine (91%)|