|Full Name||dual oxidase 1|
|Product Description||Rabbit Polyclonal antibody to DUOX1 (dual oxidase 1)|
|Background||The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]|
|Synonyms||LNOX1 antibody, MGC138840 antibody, MGC138841 antibody, NOXEF1 antibody, THOX1 antibody, DUOX1 antibody, flavoprotein NADPH oxidase antibody, large NOX 1 antibody, dual oxidase 1 antibody, thyroid oxidase 1 antibody, nicotinamide adenine dinucleotide phosphate oxidase antibody, long NOX 1 antibody, NADPH thyroid oxidase 1 antibody|
|Cellular Localization||Apical cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DUOX1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (87%), Dog (86%), Pig (90%), Bovine (90%)|