|Full Name||dynein, cytoplasmic 1, intermediate chain 2|
|Product Description||Rabbit Polyclonal antibody to DYNC1I2 (dynein, cytoplasmic 1, intermediate chain 2)|
|Background||Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.|
|Synonyms||DNCI2 antibody, FLJ21089 antibody, FLJ90842 antibody, IC2 antibody, MGC104199 antibody, MGC111094 antibody, MGC9324 antibody, DYNC1I2 antibody, cytoplasmic dynein intermediate chain 2 antibody, "dynein, cytoplasmic, intermediate polypeptide 2 antibody", DH IC-2 antibody, "dynein intermediate chain 2, cytosolic antibody", cytoplasmic dynein 1 intermediate chain 2 antibody, "dynein, cytoplasmic 1, intermediate chain 2 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DYNC1I2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (97%), Pig (98%), Chicken (94%), Rhesus Monkey (100%), Bovine (98%)|