|Full Name||dynein, cytoplasmic 1, light intermediate chain 1|
|Product Description||Rabbit Polyclonal antibody to DYNC1LI1 (dynein, cytoplasmic 1, light intermediate chain 1)|
|Background||Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores. |
|Synonyms||DNCLI1 Antibody, LIC1 Antibody, dynein, cytoplasmic 1, light intermediate chain 1 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human DYNC1LI1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (91%), Chimpanzee (99%), Bovine (95%)|