|Full Name||tumor necrosis factor receptor superfamily, member 6b, decoy|
|Product Description||Rabbit Polyclonal antibody to DcR3 (tumor necrosis factor receptor superfamily member 6B)|
|Background||This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. [provided by RefSeq]|
|Synonyms||DCR3 antibody, DJ583P15.1.1 antibody, M68 antibody, TR6 antibody, TNFRSF6B antibody, decoy receptor 3 antibody, tumor necrosis factor receptor superfamily member 6B antibody, decoy receptor for Fas ligand antibody, "tumor necrosis factor receptor superfamily, member 6b, decoy antibody"|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DcR3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (85%)|