|Full Name||C-type lectin domain family 7, member A|
|Product Description||Rabbit polyclonal antibody to Dectin-1 (C-type lectin domain family 7, member A)|
|Background||This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq]|
|Synonyms||BGR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, CLEC7A antibody, dendritic cell-associated C-type lectin 1 antibody, C-type lectin superfamily member 12 antibody, dectin-1 antibody, C-type lectin domain family 7 member A antibody, beta-glucan receptor antibody, lectin-like receptor 1 antibody, dendritic cell-associated C-type lectin-1 antibody, "C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12 antibody", DC-associated C-type lectin 1 antibody, "C-type lectin domain family 7, member A antibody"|
|Cellular Localization||Membrane , Isoform 5: Cytoplasm , Isoform 6: Cytoplasm , Isoform 7: Cytoplasm |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Dectin-1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rhesus Monkey|
|Predict Reactivity Note||Human (100%), Rhesus Monkey (100%)|