|Full Name||desmocollin 2|
|Product Description||Rabbit polyclonal antibody to Desmocollin 2 (desmocollin 2)|
|Background||The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||ARVD11 antibody, CDHF2 antibody, DG2 antibody, DGII/III antibody, DKFZp686I11137 antibody, DSC3 antibody, DSC2 antibody, desmosomal glycoprotein II antibody, cadherin family member 2 antibody, desmosomal glycoprotein III antibody, desmocollin-2 antibody, desmosomal glycoprotein II/III antibody, desmocollin 2 antibody|
|Cellular Localization||Cell membrane , Cell junction , desmosome |
|Target||Desmocollin 2 |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Desmocollin 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (80%)|