Diablo antibody [N1C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||27 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse testis|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||diablo homolog (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Smac (diablo homolog (Drosophila))|
|Background||This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq]|
|Synonyms||DIABLO-S antibody, FLJ10537 antibody, FLJ25049 antibody, SMAC antibody, SMAC3 antibody, DIABLO antibody, second mitochondria-derived activator of caspase antibody, mitochondrial Smac protein antibody, 0610041G12Rik antibody, direct IAP-binding protein with low pI antibody, "diablo homolog, mitochondrial antibody", diablo homolog (Drosophila) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Diablo. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Bovine|
|Predict Reactivity Note||Rat (84%), Dog (88%), Pig (86%), Bovine (88%)|