Dishevelled 2 antibody [N2C2], Internal
|Applications||IHC, IHC-P, WB|
Not tested in other applications.
| Immunohistochemistry||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||79 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||dishevelled, dsh homolog 2 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Dishevelled 2 (dishevelled, dsh homolog 2 (Drosophila))|
|Background||This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq]|
|Synonyms||DVL2 antibody, segment polarity protein dishevelled homolog DVL-2 antibody, dishevelled-2 antibody, DSH homolog 2 antibody, dishevelled 2 (homologous to Drosophila dsh) antibody, "dishevelled, dsh homolog 2 (Drosophila) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Dishevelled 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (99%), Zebrafish (80%), Xenopus laevis (85%), Rhesus Monkey (99%), Bovine (99%)|