|Full Name||dispatched homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Dispatched A (dispatched homolog 1 (Drosophila))|
|Background||The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq]|
|Synonyms||DISPA antibody, DKFZp434I0428 antibody, FLJ43740 antibody, MGC104180 antibody, MGC13130 antibody, MGC16796 antibody, DISP1 antibody, dispatched A antibody, protein dispatched homolog 1 antibody, dispatched homolog 1 (Drosophila) antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Dispatched A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish|
|Predict Reactivity Note||Human (100%), Mouse (91%), Rat (92%), Zebrafish (80%)|