|Full Name||dynactin 2 (p50)|
|Product Description||Rabbit Polyclonal antibody to DCTN2 (dynactin 2 (p50))|
|Background||This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]|
|Synonyms||DCTN50 antibody, DYNAMITIN antibody, RBP50 antibody, DCTN2 antibody, dynactin subunit 2 antibody, dynactin complex 50 kDa subunit antibody, 50 kD dynein-associated polypeptide antibody, dynactin complex 50 kD subunit antibody, 50 kDa dynein-associated polypeptide antibody, p50 dynamitin antibody, dynactin 2 (p50) antibody|
|Cellular Localization||Cytoplasm , cytoskeleton , Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human DCTN2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Xenopus laevis (82%), Chimpanzee (99%), Bovine (99%)|