|Full Name||dynamin 1|
|Product Description||Rabbit Polyclonal antibody to Dynamin 1 (dynamin 1)|
|Background||This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||DNM antibody, DNM1 antibody, dynamin-1 antibody, dynamin 1 antibody|
|Cellular Localization||Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Dynamin 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (92%), Dog (99%), Bovine (91%)|