|Full Name||dynamin 2|
|Product Description||Rabbit Polyclonal antibody to Dynamin 2 (dynamin 2)|
|Background||Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq]|
|Synonyms||CMT2M antibody, CMTDI1 antibody, CMTDIB antibody, DI-CMTB antibody, DYN2 antibody, DYNII antibody, DNM2 antibody, dynamin II antibody, dynamin-2 antibody, dynamin 2 antibody|
|Cellular Localization||Cytoplasm , cytoskeleton , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Dynamin 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|