Full Name | dystrobrevin, beta |
Background | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
Synonyms | MGC17163 antibody, MGC57126 antibody, DTNB antibody, dystrobrevin beta antibody, DTN-B antibody, beta-dystrobrevin antibody, dystrobrevin, beta antibody |
Cellular Localization | Cytoplasm |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human Dystrobrevin beta. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Rat, Bovine |
Predict Reactivity Note | Rat (95%), Bovine (98%) |
Conjugation | Unconjugated |