|Full Name||microtubule-associated protein, RP/EB family, member 1|
|Product Description||Rabbit polyclonal antibody to EB1 (microtubule-associated protein, RP/EB family, member 1)|
|Background||The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq]|
|Synonyms||EB1 antibody, MGC117374 antibody, MGC129946 antibody, MAPRE1 antibody, microtubule-associated protein RP/EB family member 1 antibody, APC-binding protein EB1 antibody, end-binding protein 1 antibody, adenomatous polyposis coli-binding protein EB1 antibody, "microtubule-associated protein, RP/EB family, member 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EB1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (91%), Xenopus laevis (81%), Dog (97%), Pig (97%), Chicken (85%), Rhesus Monkey (99%), Bovine (92%)|