|Full Name||proliferation-associated 2G4, 38kDa|
|Product Description||Rabbit Polyclonal antibody to EBP1 (proliferation-associated 2G4, 38kDa)|
|Background||This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq]|
|Synonyms||EBP1 antibody, HG4-1 antibody, p38-2G4 antibody, PA2G4 antibody, erbB3-binding protein 1 antibody, proliferation-associated protein 2G4 antibody, ErbB-3 binding protein 1 antibody, ErbB3-binding protein Ebp1 antibody, cell cycle protein p38-2G4 homolog antibody, "proliferation-associated 2G4, 38kDa antibody"|
|Cellular Localization||Cytoplasm , Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EBP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (97%), Chimpanzee (100%), Bovine (100%)|