|Full Name||endothelin converting enzyme-like 1|
|Product Description||Rabbit polyclonal antibody to ECEL1 (endothelin converting enzyme-like 1)|
|Background||This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. [provided by RefSeq]|
|Synonyms||DINE antibody, ECEX antibody, XCE antibody, ECEL1 antibody, X converting enzyme antibody, endothelin-converting enzyme-like 1 antibody, damage induced neuronal endopeptidase antibody, endothelin converting enzyme-like 1 antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ECEL1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (95%), Rat (95%)|