| Background | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | STHAGX1 Antibody , XHED Antibody , ODT1 Antibody , ED1 Antibody , EDA1 Antibody , HED Antibody , ED1A2 Antibody , XLHED Antibody , ECTD1 Antibody , EDA2 Antibody , ED1A1 Antibody , HED1 Antibody , EDA Antibody |