EED antibody [GT671]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||50 kDa (note)
|Positive Controls||293T , HeLa , HepG2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , C2C12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||embryonic ectoderm development|
|Product Description||Mouse Monoclonal antibody [GT671] to EED (embryonic ectoderm development)|
|Background||This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||HEED antibody, WAIT1 antibody, EED antibody, WD protein associating with integrin cytoplasmic tails 1 antibody, polycomb protein EED antibody, embryonic ectoderm development antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EED. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Japanese medaka, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (93%), Japanese medaka (95%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)|