EEN antibody [N3C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||41 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||SH3-domain GRB2-like 1|
|Product Description||Rabbit Polyclonal antibody to EEN (SH3-domain GRB2-like 1)|
|Background||This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq]|
|Synonyms||CNSA1 antibody, EEN antibody, MGC111371 antibody, SH3D2B antibody, SH3P8 antibody, SH3GL1 antibody, extra eleven-nineteen leukemia fusion gene protein antibody, endophilin-2 antibody, SH3 domain protein 2B antibody, endophilin-A2 antibody, SH3-containing Grb-2-like 1 protein antibody, SH3 domain-containing GRB2-like protein 1 antibody, extra 11-19 leukemia fusion antibody, EEN fusion partner of MLL antibody, SH3-domain GRB2-like 1 antibody|
|Cellular Localization||Cytoplasm (By similarity) , Early endosome membrane; Peripheral membrane protein (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EEN. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (87%), Chicken (85%), Bovine (93%)|