EIF2 beta antibody
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
| Immunoprecipitation||Assay-dependent dilution
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||38 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , mouse liver , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa|
|Product Description||Rabbit Polyclonal antibody to EIF2 beta (eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa)|
|Background||Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. [provided by RefSeq]|
|Synonyms||DKFZp686L18198 antibody, EIF2 antibody, EIF2B antibody, EIF2beta antibody, MGC8508 antibody, EIF2S2 antibody, eukaryotic translation initiation factor 2 subunit beta antibody, eIF-2-beta antibody, protein phosphatase 1, regulatory subunit 67 antibody, eukaryotic initiation factor 2-beta antibody, eukaryotic translation initiation factor 2 beta antibody, eukaryotic translation initiation factor 2 subunit 2 antibody, eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa antibody|
|Specificity||Knockdown/Knockout validation was supported by references (PMID:26990998)|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EIF2 beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Rabbit, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (98%), Xenopus laevis (98%), Rabbit (100%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|