| Full Name | eukaryotic translation initiation factor 3, subunit I |
| Background | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
| Synonyms | EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, EIF3I antibody, predicted protein of HQ2242 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, "eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) antibody", "eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa antibody", eukaryotic translation initiation factor 3 subunit 2 antibody, eIF-3-beta antibody, eIF3 p36 antibody, "eukaryotic translation initiation factor 3, subunit I antibody" |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human EIF3 beta. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Xenopus laevis, Pig, Rabbit, Chicken, Bovine |
| Predict Reactivity Note | Mouse (98%), Rat (98%), Xenopus laevis (88%), Pig (98%), Rabbit (96%), Chicken (92%), Bovine (98%) |
| Conjugation | Unconjugated |