|Full Name||eukaryotic translation initiation factor 3, subunit F|
|Product Description||Rabbit Polyclonal antibody to EIF3F (eukaryotic translation initiation factor 3, subunit F)|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.|
|Synonyms||EIF3S5 antibody, eIF3-p47 antibody, EIF3F antibody, "eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa antibody", eIF3-epsilon antibody, "eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) antibody", eukaryotic translation initiation factor 3 subunit F antibody, eIF-3-epsilon antibody, "eukaryotic translation initiation factor 3, subunit F antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EIF3F. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (99%), Chimpanzee (100%)|