|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||17 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||eukaryotic translation initiation factor 5A2|
|Product Description||Rabbit Polyclonal antibody to EIF5A2 (eukaryotic translation initiation factor 5A2)|
|Background||mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. |
|Synonyms||EIF-5A2 antibody, eIF5AII antibody, EIF5A2 antibody, eukaryotic translation initiation factor 5A-2 antibody, eukaryotic initiation factor 5A antibody, eIF-5A-2 antibody, eukaryotic translation initiation factor 5A2 antibody|
|Cellular Localization||Cytoplasm (By similarity) , Nucleus (By similarity) , Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) , Nucleus , nuclear pore complex (By similarity) |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human EIF5A2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)|